Pfizer Inc. Bioinformatics Scientist in Boulder, Colorado
Pfizer Boulder Research and Development is looking for a full-timebioinformatics specialist / computational biologist to work with ourDiscovery, Translational, Clinical and Commercial teams. We has a varietyof oncology programs in both targeted therapeutics and immuno-oncology thatrange from early Discovery to commercialized products. This new rolerepresents an exciting opportunity to significantly impact the discovery anddevelopment of new treatments in our integrated pipeline.Responsibilities include: Analyze and extract useful learnings from large format multidimensionaldatasets (e.g. expression, mutational, CNV and clinical outcome). Aid in the identification of new targets for Drug Discovery. Act as a primary point of contact with external consultants forpre-clinical and translational data, including delineation of scope ofwork, data formatting needs, transfer logistics, and QC for completenessand accuracy of the transferred data and analysis. Support translational programs in the identification and quantitation oftarget populations (e.g., by mutational prevalence). QC results of translational research prior to finalization in a clinicalstudy report, manuscript, abstract, etc. Mine external biomarkerdatabases and summarize findings. Aid in the design of protocols to yield results of the highest quality andvalue.Basic Qualifications Master's degree in bioinformatics, biostatistics or a closely related field 5+ years of relevant experience Fluency in Python, R and/or other relevant programming languages Knowledge of statistical methods, data mining and visualization techniques Knowledge of assembly and annotation of NGS data, including genomic andRNAseq datasets Excellent communication skills and a history of high performance andproductivityPreferred Qualifications 2-4 years of industrial experience as a bioinformaticist or closelyrelated role Knowledge of cancer genomics and public data resources Basic understanding of oncology clinical trials, endpoints,operational aspects, data handling, GCP, etc. Experience with translational medicine concepts such as clinicalbiomarkers and patient stratification Use of cloud-based analytic platforms such as DNAnexus or Quartzbio Local to Boulder locationPhysical or Mental Requirements Primarily sitting at a desk and moving through offices Ability to perform mathematical calculations and complex data analysis Light travel load No extraordinary requirementsEEO and Employment Eligibility:Pfizer is committed to equal opportunity in the terms and conditions ofemployment for all employees and job applicants without regard to race,color, religion, sex, sexual orientation, age, gender identity orgender expression, national origin, disability or veteran status. Pfizeralso complies with all applicable national, state and local laws governingnondiscrimination in employment as well as work authorization and employmenteligibility verification requirements of the Immigration and Nationality Actand IRCA. Pfizer is an E-Verify employer.